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  • Obese Women's Efforts To Get Exercise Hampered By Mental Barriers
    For arachnophobes, it's difficult to kill a spider as it scurries across the floor. Those who are scared to fly might not ever set foot on a plane. While nothing physically stops people with these aversions, a mental barrier can keep them from the task at hand. The same could be said for obese women when it comes to physical activity, according to research presented at the Obesity Society's Annual Meeting.
  • Orexigen(R) Therapeutics Presents Data On Its Proprietary Formulation Of Naltrexone Sustained Release (SR) Used In Contrave(R)
    Orexigen Therapeutics, Inc. (Nasdaq: OREX), a biopharmaceutical company focused on the treatment of obesity and other central nervous system-related disorders, presented data showing the investigational drug, Contrave(R) (naltrexone SR / bupropion SR), successfully achieved key objectives (lowered naltrexone Cmax, increased Tmax, comparable AUC) in two Phase 1 clinical trials.
  • Genaera Corporation Reports Phase 1 Data For Trodusquemine (MSI-1436) At The North American Association For The Study Of Obesity Annual Meeting
    Genaera Corporation (Nasdaq: GENR) reported data from its second Phase 1 clinical trial of trodusquemine (MSI-1436), Genaera's lead drug candidate for the treatment of type 2 diabetes and obesity. MSI-1436 is a novel inhibitor of PTP1B, a validated molecular target that controls the function of both the leptin and insulin pathways to normalize glucose and decrease appetite.
  • Concord Grape Juice Has No Significant Impact On Body Weight
    Regular consumption of 100% polyphenol-rich Concord grape juice did not cause significant weight gain, was not associated with changes in appetite and was shown to reduce waist circumference according to new data presented at the 49th Annual Meeting of the American College of Nutrition in Arlington, Virginia.
  • Obese Diners Choose Convenience And Overeating At Chinese Buffets
    When dining at Chinese Buffets, overweight individuals serve themselves and eat differently than normal weight individuals. This may lead them to overeat, according to a recent study by Cornell University's Food and Brand Lab. Compared to normal weight diners, overweight individuals sat 16 feet closer to the buffet, faced the food, used larger plates, ate with forks instead of chopsticks, and served themselves immediately instead of browsing the buffet.
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MS, RD, CDE
Headshot2006 Registered Dietitian, Certified Diabetes Educator, Wellness Nutrition & Fitness since 1992. CanyonRanch SpaClub, Las Vegas. Pediatric Dietitian. Major, USAFR. UNLV & DeVry University Instructor.

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  • Exotic Pets Risky for Kids
    The American Academy of Pediatrics and the CDC urge parents considering "nontraditional" pets to weigh the health risks those pets may pose to kids.
  • Bipolar Kids Suffer as Adults, Too
    Children who are diagnosed with bipolar disorder can continue to suffer from the disease as they develop into young adults.
  • Heart Scan May Help Predict Death
    A CT heart scan may help predict the odds of dying over the next 15 years in people with suspected coronary artery disease, new research shows.
  • Safe Blood Test for Down Syndrome
    A risk-free, early-pregnancy blood test can tell women whether their fetus has Down syndrome. The new DNA test may be available within 3 years.
  • Health Care Heats Up Presidential Race
    With a month to go before the election, health care took center stage in the presidential campaign as Barack Obama launched a major attack on John McCain's health care plan.
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  • What is benzene?

    Apple is investigating a complaint that its pre-2008 Mac Pros emit fumes from the chemical benzene. One user told Apple that he noticed a strong smell when he unpacked his Mac last year, and that 10 days later, he developed nose and throat irritation, reports the French newspaper Liberation. (A clunky English translation of the report can be found here.) [More]

  • Molecular Machines That Control Genes

    Editor's Note: This article was originally published in the February 1995 issue of Scientific American. We are reposting it this week because Robert Tijan has just been named president of the Howard Hughes Medical Institute.

    Asthma, cancer, heart disease, immune disorders and viral infections are seemingly disparate conditions. Yet they turn out to share a surprising feature. All arise to a great extent from overproduction or underproduction of one or more proteins, the molecules that carry out most reactions in the body. This realization has recently lent new urgency to research aimed at understanding, and ultimately manipulating, the fascinating biochemical machinery that regulates an essential step in protein synthesis: the transcription of genes. For a protein to be generated, the gene that specifies its composition must be transcribed, or copied, from DNA into strands of messenger RNA, which later serve as the templates from which the protein is manufactured.

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  • Plastics in Our Diet: The Need for BPA Regulation

    Studies have surfaced in recent months that certain plastic products we use every day could be interfering with our hormone systems. Approximately 100,000 synthetic chemicals are approved for consumer products and industrial processes--and certain classes of them, it seems, are dangerous to our health. One compound in the news, known as BPA, is of particular concern.

    Only a handful of once approved substances have ever become banned or severely restricted, such as DDT, PCBs and benzene. What about the rest? Under existing laws, drugs must be shown to be safe and effective, pesticides must be tested to demonstrate that they are safe enough in a balance between risks and benefits, and synthetic food additives must meet a standard set in 1958 by the Delaney Amendment to the Food, Drug and Cosmetic Act. But many, many other substances remain untouched by safety regulations.

    [More]

  • Calendar: Mind Events in October and November

    OCTOBER

    12 Face your fears at Goose Bumps! The Science of Fear, a traveling exhibition developed by the California Science Center. Kids can experience the scary emotion in a safe environment as they learn how their brain and body work together to confront danger. Visit Boston’s Museum of Science to get your heart pumping in hands-on activities, including an interactive video game where the player learns how fear helps animals survive in nature. [More]

  • Cocaine Addiction Stems from Desire, Not the Drug

    Scientists know that addictive drugs can mess with the brain’s circuitry and hijack its reward systems, but a July 31 rat study in the journal Neuron shows that psychological factors may be more instrumental in causing these changes than a drug’s chemical effects are. Cocaine use triggers long-lasting cellular memories in the brain, the study found--but only if the user consumes the drug voluntarily.

    A team led by Billy Chen and Antonello Bonci, both at the University of California, San Francisco, trained three groups of rats to press levers that delivered cocaine, food or sugar. The researchers injected cocaine into a fourth group. When they examined the rats’ brain tissue, they found an increase in synaptic strength within the reward center in those rats that had self-administered sugar, food or cocaine. These cellular memories were short-lived in the sugar and food groups, but in rats that had self-administered cocaine they persisted for up to three months after consumption had stopped. Most interestingly, the brains of rats that had consumed cocaine involuntarily did not show such imprints.

    [More]

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